ADRM1
Gene Ontology Biological Process
- Sertoli cell development [IMP]
- adipose tissue development [IMP]
- follicle-stimulating hormone signaling pathway [IMP]
- oogenesis [IMP]
- ovarian follicle development [IMP]
- positive regulation of endopeptidase activity [ISO]
- positive regulation of growth hormone receptor signaling pathway [IMP]
- proteasome assembly [ISO]
- regulation of T cell differentiation in thymus [IMP]
- seminiferous tubule development [IMP]
- spermatid development [IMP]
- thymus development [IMP]
- transcription elongation from RNA polymerase II promoter [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
UBC
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Reconstituted Complex
An interaction is detected between purified proteins in vitro.
Publication
Proteasome subunit Rpn13 is a novel ubiquitin receptor.
Proteasomal receptors that recognize ubiquitin chains attached to substrates are key mediators of selective protein degradation in eukaryotes. Here we report the identification of a new ubiquitin receptor, Rpn13/ARM1, a known component of the proteasome. Rpn13 binds ubiquitin through a conserved amino-terminal region termed the pleckstrin-like receptor for ubiquitin (Pru) domain, which binds K48-linked diubiquitin with an affinity of approximately ... [more]
Throughput
- Low Throughput
Additional Notes
- #LPPI
- Likely protein-protein interaction
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| UBC ADRM1 | Reconstituted Complex Reconstituted Complex An interaction is detected between purified proteins in vitro. | High | - | BioGRID | 2297284 | |
| ADRM1 UBC | Two-hybrid Two-hybrid Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation. | Low | - | BioGRID | 617472 |
Curated By
- BioGRID