PRKCG
Gene Ontology Biological Process
- chemosensory behavior [IMP]
- innervation [IMP]
- negative regulation of neuron apoptotic process [ISO]
- negative regulation of proteasomal protein catabolic process [IMP]
- negative regulation of protein catabolic process [ISO]
- negative regulation of protein ubiquitination [IMP, ISO]
- phosphorylation [ISO]
- positive regulation of mismatch repair [ISO]
- protein autophosphorylation [ISO]
- regulation of circadian rhythm [IMP]
- regulation of response to food [IMP]
- response to morphine [IMP]
- response to pain [IMP]
- synaptic transmission [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Affinity Capture-Western
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins.
Publication
Cypher, a striated muscle-restricted PDZ and LIM domain-containing protein, binds to alpha-actinin-2 and protein kinase C.
We have cloned and characterized a novel striated muscle-restricted protein (Cypher) that has two mRNA splice variants, designated Cypher1 and Cypher2. Both proteins contain an amino-terminal PDZ domain. Cypher1, but not Cypher2, contains three carboxyl-terminal LIM domains and an amino acid repeat sequence that exhibits homology to a repeat sequence found in the largest subunit of RNA polymerase II. cypher1 ... [more]
Throughput
- Low Throughput
Curated By
- BioGRID