BAIT
FGF3
HBGF-3, INT2
fibroblast growth factor 3
GO Process (12)
GO Function (1)
GO Component (1)
Gene Ontology Biological Process
- Fc-epsilon receptor signaling pathway [TAS]
- anatomical structure morphogenesis [TAS]
- cell-cell signaling [TAS]
- epidermal growth factor receptor signaling pathway [TAS]
- fibroblast growth factor receptor signaling pathway [IGI, TAS]
- innate immune response [TAS]
- insulin receptor signaling pathway [TAS]
- negative regulation of cardiac muscle tissue development [IMP]
- neurotrophin TRK receptor signaling pathway [TAS]
- phosphatidylinositol-mediated signaling [TAS]
- positive regulation of cell proliferation [IGI]
- signal transduction [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
RPS2
LLREP3, S2
ribosomal protein S2
GO Process (14)
GO Function (6)
GO Component (9)
Gene Ontology Biological Process
- RNA metabolic process [TAS]
- SRP-dependent cotranslational protein targeting to membrane [TAS]
- cellular protein metabolic process [TAS]
- gene expression [TAS]
- mRNA metabolic process [TAS]
- nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [TAS]
- positive regulation of transferase activity [IDA]
- translation [IC, TAS]
- translational elongation [TAS]
- translational initiation [TAS]
- translational termination [TAS]
- viral life cycle [TAS]
- viral process [TAS]
- viral transcription [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
Fibroblast growth factor 3, a protein with a dual subcellular fate, is interacting with human ribosomal protein S2.
The secreted isoform of fibroblast growth factor 3 (FGF3) induces a mitogenic cell response, while the nuclear form inhibits cell proliferation. Recently, we identified a nucleolar FGF3-binding protein which is implicated in processing of pre-rRNA as a possible target of nuclear FGF3 signalling. Here, we report a second candidate protein identified by a yeast two-hybrid screen for nuclear FGF3 action, ... [more]
Biochem. Biophys. Res. Commun. Dec. 16, 2005; 338(2);1248-55 [Pubmed: 16263090]
Throughput
- Low Throughput
Curated By
- BioGRID