BAIT
BPTF
9430093H17Rik, Falz, RP23-317F9.3
bromodomain PHD finger transcription factor
GO Process (10)
GO Function (3)
GO Component (9)
Gene Ontology Biological Process
- ATP catabolic process [ISO]
- anterior/posterior pattern specification [IMP]
- brain development [ISO]
- chromatin remodeling [ISO]
- embryonic placenta development [IMP]
- endoderm development [IMP]
- negative regulation of transcription from RNA polymerase II promoter [ISO]
- positive regulation of transcription, DNA-templated [ISO]
- regulation of transcription, DNA-templated [ISO]
- transcription, DNA-templated [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
SRF
AW049942, AW240594
serum response factor
GO Process (68)
GO Function (16)
GO Component (4)
Gene Ontology Biological Process
- actin cytoskeleton organization [IMP]
- actin filament organization [IMP]
- associative learning [IMP]
- bronchus cartilage development [IMP]
- cardiac myofibril assembly [IMP]
- cardiac vascular smooth muscle cell differentiation [IMP]
- cell migration involved in sprouting angiogenesis [IMP, ISO]
- cell-matrix adhesion [IMP]
- cellular senescence [ISO]
- contractile actin filament bundle assembly [IMP]
- developmental growth [IMP]
- dorsal aorta morphogenesis [IMP]
- epithelial cell-cell adhesion [IMP]
- epithelial structure maintenance [IMP]
- erythrocyte development [IMP]
- eyelid development in camera-type eye [IMP]
- gastrulation [IMP]
- heart development [IMP]
- heart looping [IMP]
- heart trabecula formation [IMP]
- hematopoietic stem cell differentiation [IMP]
- hippocampus development [IMP]
- in utero embryonic development [IMP]
- leukocyte differentiation [IMP]
- long term synaptic depression [IMP]
- long-term memory [ISO]
- lung morphogenesis [IMP]
- lung smooth muscle development [IMP]
- mRNA transcription from RNA polymerase II promoter [IDA]
- megakaryocyte development [IMP]
- mesoderm formation [IMP]
- morphogenesis of an epithelial sheet [IMP]
- muscle cell cellular homeostasis [IMP]
- negative regulation of beta-amyloid clearance [ISO]
- negative regulation of cell migration [ISO]
- negative regulation of cell proliferation [ISO]
- neuron migration [IMP]
- neuron projection development [IMP]
- patterning of blood vessels [IMP]
- platelet activation [IMP]
- platelet formation [IMP]
- positive regulation of axon extension [IGI, IMP]
- positive regulation of cell differentiation [ISO]
- positive regulation of filopodium assembly [IMP]
- positive regulation of sequence-specific DNA binding transcription factor activity [ISO]
- positive regulation of smooth muscle contraction [ISO]
- positive regulation of transcription by glucose [ISO]
- positive regulation of transcription from RNA polymerase II promoter [IDA, IGI, IMP, ISO]
- positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation [IMP, ISO]
- positive regulation of transcription initiation from RNA polymerase II promoter [ISO]
- positive regulation of transcription via serum response element binding [ISO]
- positive regulation of transcription, DNA-templated [IMP, ISO]
- positive thymic T cell selection [IMP]
- primitive streak formation [IMP]
- regulation of cell adhesion [IMP]
- regulation of transcription, DNA-templated [IDA]
- regulation of water loss via skin [IMP]
- response to cytokine [ISO]
- response to hormone [ISO]
- sarcomere organization [IMP]
- single organismal cell-cell adhesion [IMP]
- skin morphogenesis [IMP]
- stress fiber assembly [IMP]
- tangential migration from the subventricular zone to the olfactory bulb [IMP]
- tight junction assembly [IMP]
- trachea cartilage development [IMP]
- transcription from RNA polymerase II promoter [ISO]
- trophectodermal cell differentiation [ISO]
Gene Ontology Molecular Function- DNA binding [IDA, IGI]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding [IDA]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription [IDA, ISO]
- RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity [ISO]
- RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity [IDA]
- RNA polymerase II transcription factor binding transcription factor activity [IDA]
- RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription [IDA]
- chromatin DNA binding [IDA]
- chromatin binding [IDA]
- histone deacetylase binding [ISO]
- protein binding [IPI]
- protein homodimerization activity [ISO]
- sequence-specific DNA binding [ISO]
- sequence-specific DNA binding transcription factor activity [IDA, ISO]
- serum response element binding [IDA, ISO]
- transcription factor binding [ISO]
- DNA binding [IDA, IGI]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding [IDA]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription [IDA, ISO]
- RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity [ISO]
- RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity [IDA]
- RNA polymerase II transcription factor binding transcription factor activity [IDA]
- RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription [IDA]
- chromatin DNA binding [IDA]
- chromatin binding [IDA]
- histone deacetylase binding [ISO]
- protein binding [IPI]
- protein homodimerization activity [ISO]
- sequence-specific DNA binding [ISO]
- sequence-specific DNA binding transcription factor activity [IDA, ISO]
- serum response element binding [IDA, ISO]
- transcription factor binding [ISO]
Mus musculus
Affinity Capture-Western
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins.
Publication
Chromatin remodeling complex NURF regulates thymocyte maturation.
The maturation of T cells requires signaling from both cytokine and T-cell receptors to gene targets in chromatin, but how chromatin architecture influences this process is largely unknown. Here we show that thymocyte maturation post-positive selection is dependent on the nucleosome remodeling factor (NURF). Depletion of Bptf (bromodomain PHD finger transcription factor), the largest NURF subunit, in conditional mouse mutants ... [more]
Genes Dev. Feb. 01, 2011; 25(3);275-86 [Pubmed: 21289071]
Throughput
- Low Throughput
Curated By
- BioGRID