UBC
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
XIAP
Gene Ontology Biological Process
- cellular response to DNA damage stimulus [ISO]
- inhibition of cysteine-type endopeptidase activity involved in apoptotic process [IBA, ISO]
- negative regulation of apoptotic process [IMP, ISO, TAS]
- negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [ISO]
- negative regulation of neuron apoptotic process [IDA, IMP]
- neuron apoptotic process [ISO]
- positive regulation of canonical Wnt signaling pathway [IBA, ISO]
- positive regulation of protein linear polyubiquitination [ISO]
- positive regulation of protein ubiquitination [ISO]
- protein ubiquitination [IBA, ISO]
- spindle assembly involved in mitosis [IBA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Affinity Capture-Western
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins.
Publication
Monoubiquitination and cellular distribution of XIAP in neurons after traumatic brain injury.
XIAP is a member of the inhibitor of apoptosis (IAP) gene family that, in addition to suppressing cell death by inhibition and polyubiquitination of caspases, is involved in an increasing number of signaling cascades. Moreover, the function and regulation of XIAP in the central nervous system (CNS) is poorly understood. In this study, the authors investigated the cell-type expression, the ... [more]
Throughput
- Low Throughput
Curated By
- BioGRID