BAIT
SMAD9
MADH6, Madh8, Madh9, Smad8
SMAD family member 9
GO Process (10)
GO Function (1)
GO Component (3)
Gene Ontology Biological Process
- BMP signaling pathway [IDA, IGI]
- Mullerian duct regression [ISO]
- bone development [IGI]
- cartilage development [IGI]
- cellular response to organic cyclic compound [IDA]
- hindbrain development [IMP]
- midbrain development [IMP]
- positive regulation of cell differentiation [ISO]
- positive regulation of transcription, DNA-templated [ISO]
- protein phosphorylation [IDA]
Gene Ontology Molecular Function
Mus musculus
PREY
PSMC3
TBP-1, RP23-263H8.1
proteasome (prosome, macropain) 26S subunit, ATPase 3
GO Process (1)
GO Function (0)
GO Component (7)
Gene Ontology Biological Process
Gene Ontology Cellular Component
Mus musculus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
SMAD 8 binding to mice Msx1 basal promoter is required for transcriptional activation.
The Msx1 gene in mice has been proven to be induced by BMP (bone morphogenetic protein) proteins, and three binding sites for SMAD, an intracellular BMP signalling transducer, have already been identified in its promoter. Gel shift analyses were performed and they demonstrated that the consensus found very near the transcription start site, a region designed BP (basal promoter), is ... [more]
Biochem. J. Jan. 01, 2006; 393(0);141-50 [Pubmed: 16101586]
Throughput
- Low Throughput
Curated By
- BioGRID