BAIT
CTCF
AW108038
CCCTC-binding factor
GO Process (17)
GO Function (10)
GO Component (5)
Gene Ontology Biological Process
- DNA methylation [IDA, IMP]
- dosage compensation by inactivation of X chromosome [TAS]
- maintenance of DNA methylation [IMP]
- negative regulation of gene expression [IMP]
- negative regulation of transcription from RNA polymerase II promoter [IMP, ISO]
- negative regulation of transcription, DNA-templated [ISO]
- nucleosome positioning [ISO]
- positive regulation of gene expression [IMP, ISO]
- positive regulation of transcription from RNA polymerase II promoter [IDA]
- positive regulation of transcription, DNA-templated [ISO]
- regulation of gene expression by genetic imprinting [IDA, IMP]
- regulation of gene expression, epigenetic [ISO]
- regulation of histone acetylation [IMP]
- regulation of histone methylation [IMP]
- regulation of molecular function, epigenetic [ISO]
- regulation of transcription, DNA-templated [IDA]
- transcription from RNA polymerase II promoter [IDA]
Gene Ontology Molecular Function- DNA binding [IDA]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding [ISO]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription [ISO]
- RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription [IDA]
- chromatin binding [IDA]
- chromatin insulator sequence binding [ISO]
- protein binding [IPI]
- sequence-specific DNA binding [ISO]
- sequence-specific DNA binding transcription factor activity [ISO]
- transcription regulatory region DNA binding [ISO]
- DNA binding [IDA]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding [ISO]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription [ISO]
- RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription [IDA]
- chromatin binding [IDA]
- chromatin insulator sequence binding [ISO]
- protein binding [IPI]
- sequence-specific DNA binding [ISO]
- sequence-specific DNA binding transcription factor activity [ISO]
- transcription regulatory region DNA binding [ISO]
Gene Ontology Cellular Component
Mus musculus
PREY
CD3EAP
1190028F09, 2610103M17Rik, ASE-1, Ase1, CAST, PAF49
CD3E antigen, epsilon polypeptide associated protein
GO Process (1)
GO Function (2)
GO Component (5)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Mus musculus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
CTCF regulates the local epigenetic state of ribosomal DNA repeats.
CCCTC binding factor (CTCF) is a highly conserved zinc finger protein, which is involved in chromatin organization, local histone modifications, and RNA polymerase II-mediated gene transcription. CTCF may act by binding tightly to DNA and recruiting other proteins to mediate its various functions in the nucleus. To further explore the role of this essential factor, we used a mass spectrometry-based ... [more]
Epigenetics Chromatin Nov. 10, 2010; 3(1);19 [Pubmed: 21059229]
Throughput
- Low Throughput
Curated By
- BioGRID