BAIT
CRKL
v-crk avian sarcoma virus CT10 oncogene homolog-like
GO Process (5)
GO Function (4)
GO Component (3)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Homo sapiens
PREY
LTBP4
ARCL1C, LTBP-4, LTBP4L, LTBP4S
latent transforming growth factor beta binding protein 4
GO Process (8)
GO Function (6)
GO Component (5)
Gene Ontology Biological Process
- extracellular matrix organization [TAS]
- growth hormone secretion [TAS]
- multicellular organismal development [TAS]
- protein folding [TAS]
- regulation of cell differentiation [TAS]
- regulation of cell growth [TAS]
- regulation of proteolysis [IDA]
- regulation of transforming growth factor beta receptor signaling pathway [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
Identification of multi-SH3 domain-containing protein interactome in pancreatic cancer: a yeast two-hybrid approach.
Pancreatic ductal adenocarcinoma (PDAC) is a fatal disease that shows minimal response to chemotherapy. Genetic changes involved in the progression of PDAC concern genes that encode proteins related to signal transduction networks. This fact reveals the importance in identifying the role and the relations between multiple signaling cascades in PDAC. One of the major factors that modulate signaling events is ... [more]
Proteomics Aug. 01, 2008; 8(15);3071-81 [Pubmed: 18654987]
Throughput
- Low Throughput
Curated By
- BioGRID