BAIT

MFA1

L000001096, YDR461W
Mating pheromone a-factor; made by a cells; interacts with alpha cells to induce cell cycle arrest and other responses leading to mating; biogenesis involves C-terminal modification, N-terminal proteolysis, and export; also encoded by MFA2
GO Process (1)
GO Function (1)
GO Component (1)

Gene Ontology Biological Process

Gene Ontology Molecular Function

Gene Ontology Cellular Component

Saccharomyces cerevisiae (S288c)
PREY

MFA2

L000001097, YNL145W
Mating pheromone a-factor; made by a cells; interacts with alpha cells to induce cell cycle arrest and other responses leading to mating; biogenesis involves C-terminal modification, N-terminal proteolysis, and export; also encoded by MFA1
GO Process (1)
GO Function (1)
GO Component (1)

Gene Ontology Biological Process

Gene Ontology Molecular Function

Gene Ontology Cellular Component

Saccharomyces cerevisiae (S288c)

Phenotypic Enhancement

A genetic interaction is inferred when mutation or overexpression of one gene results in enhancement of any phenotype (other than lethality/growth defect) associated with mutation or over expression of another gene.

Publication

Molecular quantification of Saccharomyces cerevisiae α-pheromone secretion.

Rogers DW, McConnell E, Greig D

SUMMARY: Saccharomyces cerevisiae yeast cells court each other by producing an attractive sex pheromone specific to their mating-type. Cells detect the sex pheromone from potential mates using a well-defined intracellular signaling cascade that has become a model for studying signal transduction. In contrast, the factors contributing to production of pheromone itself are poorly characterized, despite the widespread use of the ... [more]

Unknown Jun. 04, 2012; 0(0); [Pubmed: 22672638]

Throughput

  • Low Throughput

Ontology Terms

  • phenotype: pheromone production (APO:0000036)

Additional Notes

  • double mutants are unable to produce pheromone

Curated By

  • BioGRID