SID2
Gene Ontology Biological Process
- maintenance of endoplasmic reticulum location involved in endoplasmic reticulum polarization at cell division site [IMP]
- negative regulation of protein homooligomerization [IMP]
- negative regulation of protein localization to microtubule [IMP]
- positive regulation of mitotic spindle elongation [IMP]
- positive regulation of nuclear migration during mitotic telophase [IMP]
- positive regulation of septation initiation signaling [IMP]
- regulation of mitotic cytokinesis [IMP]
- septation initiation signaling [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
SID4
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
The fission yeast SIN kinase, Sid2, is required for SIN asymmetry and regulates the SIN scaffold, Cdc11.
The Schizosaccharomyces pombe septation initiation network (SIN) is a Spg1-GTPase mediated protein kinase cascade that triggers actomyosin ring constriction, septation, and cell division. The SIN is assembled at the spindle pole body (SPB) on the scaffold proteins Cdc11 and Sid4, with Cdc11 binding directly to SIN signaling components. Proficient SIN activity requires the asymmetric distribution of its signaling components to ... [more]
Throughput
- Low Throughput
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| SID4 SID2 | Synthetic Lethality Synthetic Lethality A genetic interaction is inferred when mutations or deletions in separate genes, each of which alone causes a minimal phenotype, result in lethality when combined in the same cell under a given condition. | Low | - | BioGRID | 246403 | |
| SID2 SID4 | Synthetic Lethality Synthetic Lethality A genetic interaction is inferred when mutations or deletions in separate genes, each of which alone causes a minimal phenotype, result in lethality when combined in the same cell under a given condition. | Low | - | BioGRID | 796915 |
Curated By
- BioGRID