BAIT
ELAVL1
ELAV1, HUR, Hua, MelG
ELAV like RNA binding protein 1
GO Process (8)
GO Function (9)
GO Component (5)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Homo sapiens
PREY
OSR2
odd-skipped related transciption factor 2
GO Process (26)
GO Function (1)
GO Component (1)
Gene Ontology Biological Process
- bone morphogenesis [ISS]
- cell differentiation [ISS]
- chondrocyte differentiation [ISS]
- embryo development [ISS]
- embryonic digit morphogenesis [ISS]
- embryonic forelimb morphogenesis [ISS]
- embryonic hindlimb morphogenesis [ISS]
- embryonic skeletal joint development [ISS]
- embryonic skeletal joint morphogenesis [ISS]
- embryonic skeletal limb joint morphogenesis [ISS]
- embryonic skeletal system morphogenesis [ISS]
- eyelid development in camera-type eye [ISS]
- head development [ISS]
- mesonephros development [ISS]
- metanephros development [ISS]
- middle ear morphogenesis [ISS]
- negative regulation of transcription from RNA polymerase II promoter [ISS]
- odontogenesis [ISS]
- osteoblast proliferation [ISS]
- palate development [ISS]
- positive regulation of bone mineralization [ISS]
- positive regulation of cell proliferation [ISS]
- positive regulation of epithelial cell proliferation [ISS]
- positive regulation of gene expression [ISS]
- positive regulation of transcription from RNA polymerase II promoter [ISS]
- positive regulation of transcription, DNA-templated [ISS]
Gene Ontology Molecular Function
Homo sapiens
Affinity Capture-RNA
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and associated RNA species identified by Northern blot, RT-PCR, affinity labeling, sequencing, or microarray analysis.
Publication
Ubiquitin-mediated proteolysis of HuR by heat shock.
The RNA-binding protein HuR regulates the stability and translation of numerous mRNAs encoding stress-response and proliferative proteins. Although its post-transcriptional influence has been linked primarily to its cytoplasmic translocation, here we report that moderate heat shock (HS) potently reduces HuR levels, thereby altering the expression of HuR target mRNAs. HS did not change HuR mRNA levels or de novo translation, ... [more]
EMBO J. May. 06, 2009; 28(9);1271-82 [Pubmed: 19322201]
Throughput
- High Throughput
Ontology Terms
- cell line: hela cell (BTO:0000567) [cervical adenocarcinoma (DOID:3702)]
Curated By
- BioGRID