BAIT
ELAVL1
ELAV1, HUR, Hua, MelG
ELAV like RNA binding protein 1
GO Process (8)
GO Function (9)
GO Component (5)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Homo sapiens
PREY
MYADM
SB135, UNQ553/PRO1110
myeloid-associated differentiation marker
GO Process (12)
GO Function (0)
GO Component (6)
Gene Ontology Biological Process
- cell-cell junction maintenance [IMP]
- establishment of endothelial barrier [IMP]
- membrane raft organization [IMP]
- negative regulation of actin filament polymerization [IMP]
- negative regulation of gene expression [IMP]
- negative regulation of heterotypic cell-cell adhesion [IDA]
- negative regulation of protein kinase C signaling [IMP]
- negative regulation of protein phosphorylation [IMP]
- positive regulation of cell migration [IMP]
- positive regulation of substrate adhesion-dependent cell spreading [IMP]
- protein targeting to plasma membrane [IMP]
- regulation of cell-substrate adhesion [IMP]
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-RNA
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and associated RNA species identified by Northern blot, RT-PCR, affinity labeling, sequencing, or microarray analysis.
Publication
Ubiquitin-mediated proteolysis of HuR by heat shock.
The RNA-binding protein HuR regulates the stability and translation of numerous mRNAs encoding stress-response and proliferative proteins. Although its post-transcriptional influence has been linked primarily to its cytoplasmic translocation, here we report that moderate heat shock (HS) potently reduces HuR levels, thereby altering the expression of HuR target mRNAs. HS did not change HuR mRNA levels or de novo translation, ... [more]
EMBO J. May. 06, 2009; 28(9);1271-82 [Pubmed: 19322201]
Throughput
- High Throughput
Ontology Terms
- hela cell (BTO:0000567) [cervical adenocarcinoma (DOID:3702)]
Curated By
- BioGRID