Biochemical Activity (Phosphorylation)

An interaction is inferred from the biochemical effect of one protein upon another, for example, GTP-GDP exchange activity or phosphorylation of a substrate by a kinase. The bait protein executes the activity on the substrate hit protein. A Modification value is recorded for interactions of this type with the possible values Phosphorylation, Ubiquitination, Sumoylation, Dephosphorylation, Methylation, Prenylation, Acetylation, Deubiquitination, Proteolytic Processing, Glucosylation, Nedd(Rub1)ylation, Deacetylation, No Modification, Demethylation.

Publication

Interacting factors and cellular localization of SR protein-specific kinase Dsk1.

Tang Z, Luca M, Taggart-Murphy L, Portillio J, Chang C, Guven A, Lin RJ, Murray J, Carr A

Schizosaccharomyces pombe Dsk1 is an SR protein-specific kinase (SRPK), whose homologs have been identified in every eukaryotic organism examined. Although discovered as a mitotic regulator with protein kinase activity toward SR splicing factors, it remains largely unknown about what and how Dsk1 contributes to cell cycle and pre-mRNA splicing. In this study, we investigated the Dsk1 function by determining interacting ... [more]

Unknown Jun. 06, 2012; 0(0); [Pubmed: 22683458]

Throughput

  • Low Throughput

Additional Notes

  • figure 3A.

Related interactions

InteractionExperimental Evidence CodeDatasetThroughputScoreCurated ByNotes
CIA1 DSK1
Synthetic Lethality
Synthetic Lethality

A genetic interaction is inferred when mutations or deletions in separate genes, each of which alone causes a minimal phenotype, result in lethality when combined in the same cell under a given condition.

Low-BioGRID
635467

Curated By

  • BioGRID