BAIT

FAR8

SPBC1773.01, csc3, SPBC1773.01
SIP/FAR complex striatin subunit, Far8/Csc3
Schizosaccharomyces pombe (972h)
PREY

CHC1

SPAC26A3.05
clathrin heavy chain Chc1 (predicted)
GO Process (2)
GO Function (1)
GO Component (2)

Gene Ontology Biological Process

Gene Ontology Molecular Function

Gene Ontology Cellular Component

Schizosaccharomyces pombe (972h)

Affinity Capture-MS

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.

Publication

SIN-inhibitory phosphatase complex promotes Cdc11p dephosphorylation and propagates SIN asymmetry in fission yeast.

Singh NS, Shao N, McLean JR, Sevugan M, Ren L, Chew TG, Bimbo A, Sharma R, Tang X, Gould KL, Balasubramanian MK

Cytokinesis in many eukaryotes involves the function of an actomyosin-based contractile ring. In fission yeast, actomyosin ring maturation and stability require a conserved signaling pathway termed the SIN (septation initiation network). The SIN consists of a GTPase (Spg1p) and three protein kinases, all of which localize to the mitotic spindle pole bodies (SPBs). Two of the SIN kinases, Cdc7p and ... [more]

Curr. Biol. Dec. 06, 2011; 21(23);1968-78 [Pubmed: 22119525]

Throughput

  • High Throughput

Curated By

  • BioGRID