YWHAQ
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
PDE3B
Gene Ontology Biological Process
- blood coagulation [TAS]
- cAMP catabolic process [IEP]
- cellular response to insulin stimulus [ISS]
- insulin receptor signaling pathway [TAS]
- negative regulation of angiogenesis [IMP]
- negative regulation of cAMP-mediated signaling [IC]
- negative regulation of cell adhesion [IMP]
- negative regulation of cell adhesion mediated by integrin [IC]
- negative regulation of lipid catabolic process [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Protein-peptide
An interaction is detected between a protein and a peptide derived from an interaction partner. This includes phage display experiments.
Publication
Sequence-Specific Recognition of a PxLPxI/L Motif by an Ankyrin Repeat Tumbler Lock.
Ankyrin repeat family A protein 2 (ANKRA2) interacts with the plasma membrane receptor megalin and the class IIa histone deacetylases HDAC4 and HDAC5. We report that the ankyrin repeat domains of ANKRA2 and its close paralog regulatory factor X-associated ankyrin-containing protein (RFXANK) recognize a PxLPxI/L motif found in diverse binding proteins, including HDAC4, HDAC5, HDAC9, megalin, and regulatory factor X, ... [more]
Throughput
- Low Throughput
Additional Notes
- figure 7A. phosphorylated peptides (PS/TLP consensus).
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| YWHAQ PDE3B | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | High | 0.9933 | BioGRID | 3236686 |
Curated By
- BioGRID