BAIT
SLC2A4
GLUT4
solute carrier family 2 (facilitated glucose transporter), member 4
GO Process (9)
GO Function (2)
GO Component (8)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
STRN3
SG2NA
striatin, calmodulin binding protein 3
GO Process (5)
GO Function (6)
GO Component (9)
Gene Ontology Biological Process
- negative regulation of intracellular estrogen receptor signaling pathway [ISS]
- negative regulation of transcription from RNA polymerase II promoter [IDA]
- negative regulation of transcription, DNA-templated [IDA]
- positive regulation of transcription from RNA polymerase II promoter [IDA]
- response to estradiol [ISS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Insulin-dependent interactions of proteins with GLUT4 revealed through stable isotope labeling by amino acids in cell culture (SILAC).
The insulin-regulated glucose transporter (GLUT4) translocates to the plasma membrane in response to insulin in order to facilitate the postprandial uptake of glucose into fat and muscle cells. While early insulin receptor signaling steps leading to this translocation are well defined, the integration of signaling and regulation of GLUT4 traffic remains elusive. Several lines of evidence suggest an important role ... [more]
J. Proteome Res. Jan. 01, 2006; 5(1);64-75 [Pubmed: 16396496]
Throughput
- Low Throughput
Curated By
- BioGRID