RNF2
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
CSNK2A1
Gene Ontology Biological Process
- mitotic spindle checkpoint [ISO]
- negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [ISO]
- positive regulation of Wnt signaling pathway [ISO]
- positive regulation of cell growth [ISO]
- positive regulation of cell proliferation [ISO]
- positive regulation of protein catabolic process [ISO]
- protein autophosphorylation [IDA]
- protein phosphorylation [IDA, ISO]
- regulation of catalytic activity [IDA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
PRC1 and PRC2 are not required for targeting of H2A.Z to developmental genes in embryonic stem cells.
The essential histone variant H2A.Z localises to both active and silent chromatin sites. In embryonic stem cells (ESCs), H2A.Z is also reported to co-localise with polycomb repressive complex 2 (PRC2) at developmentally silenced genes. The mechanism of H2A.Z targeting is not clear, but a role for the PRC2 component Suz12 has been suggested. Given this association, we wished to determine ... [more]
Throughput
- High Throughput
Additional Notes
- figure 1, table S1.
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| RNF2 CSNK2A1 | Affinity Capture-Western Affinity Capture-Western An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins. | Low | - | BioGRID | - |
Curated By
- BioGRID