BAIT
TRAF4
CART1, MLN62, RNF83
TNF receptor-associated factor 4
GO Process (4)
GO Function (6)
GO Component (2)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Homo sapiens
PREY
FTH1
FHC, FTH, FTHL6, HFE5, PIG15, PLIF, OK/SW-cl.84
ferritin, heavy polypeptide 1
GO Process (8)
GO Function (2)
GO Component (4)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
Identification and characterization of proteins interacting with Traf4, an enigmatic p53 target.
Tumor necrosis factor receptor associated factor 4 (Traf4) mRNA expression is upregulated in various breast tumors and tumor cell lines. We previously identified Traf4 as a p53 target gene, and showed overexpression of Traf4 inhibited colony formation. However, basal Traf4 expression in cell lines does not appear to be dependent entirely on p53. To address the putative function of Traf4, ... [more]
Cancer Biol. Ther. Sep. 01, 2006; 5(9);1228-35 [Pubmed: 16969126]
Throughput
- Low Throughput
Curated By
- BioGRID