HNRNPA1
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
ADAR
Gene Ontology Biological Process
- adenosine to inosine editing [IDA, IMP, TAS]
- base conversion or substitution editing [IDA]
- cytokine-mediated signaling pathway [TAS]
- gene expression [TAS]
- innate immune response [TAS]
- mRNA modification [TAS]
- miRNA loading onto RISC involved in gene silencing by miRNA [IDA]
- negative regulation of protein kinase activity by regulation of protein phosphorylation [IDA, IMP]
- positive regulation of viral genome replication [IDA, IMP]
- pre-miRNA processing [IDA]
- protein export from nucleus [IDA]
- protein import into nucleus [IDA]
- response to interferon-alpha [IDA]
- response to virus [IMP]
- type I interferon signaling pathway [TAS]
Gene Ontology Molecular Function
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
DBIRD complex integrates alternative mRNA splicing with RNA polymerase II transcript elongation.
Alternative messenger RNA splicing is the main reason that vast mammalian proteomic complexity can be achieved with a limited number of genes. Splicing is physically and functionally coupled to transcription, and is greatly affected by the rate of transcript elongation. As the nascent pre-mRNA emerges from transcribing RNA polymerase II (RNAPII), it is assembled into a messenger ribonucleoprotein (mRNP) particle; ... [more]
Throughput
- High Throughput
Additional Notes
- figure 1, S2.
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| HNRNPA1 ADAR | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | High | - | BioGRID | 1442981 | |
| HNRNPA1 ADAR | Proximity Label-MS Proximity Label-MS An interaction is inferred when a bait-enzyme fusion protein selectively modifies a vicinal protein with a diffusible reactive product, followed by affinity capture of the modified protein and identification by mass spectrometric methods. | High | 3.14 | BioGRID | 2990338 |
Curated By
- BioGRID