BAIT

SH3KBP1

CD2BP3, CIN85, GIG10, HSB-1, HSB1, MIG18, RP11-345L8.1
SH3-domain kinase binding protein 1
UPS Project
Homo sapiens
PREY

SEPT2

DIFF6, NEDD-5, NEDD5, Pnutl3, hNedd5
septin 2
GO Process (2)
GO Function (1)
GO Component (8)

Gene Ontology Biological Process

Gene Ontology Molecular Function

Gene Ontology Cellular Component

Homo sapiens

Affinity Capture-MS

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.

Publication

Proteins recruited by SH3 domains of Ruk/CIN85 adaptor identified by LC-MS/MS.

Havrylov S, Rzhepetskyy Y, Malinowska A, Drobot L, Redowicz MJ

Ruk/CIN85 is a mammalian adaptor molecule with three SH3 domains. Using its SH3 domains Ruk/CIN85 can cluster multiple proteins and protein complexes, and, consequently, facilitates organisation of elaborate protein interaction networks with diverse regulatory roles. Previous research linked Ruk/CIN85 with the regulation of vesicle-mediated transport and cancer cell invasiveness. Despite the recent findings, precise molecular functions of Ruk/CIN85 in these ... [more]

Proteome Sci Jun. 18, 2009; 7(0);21 [Pubmed: 19531213]

Throughput

  • Low Throughput

Related interactions

InteractionExperimental Evidence CodeDatasetThroughputScoreCurated ByNotes
SH3KBP1 SEPT2
Reconstituted Complex
Reconstituted Complex

An interaction is detected between purified proteins in vitro.

Low-BioGRID
1241621

Curated By

  • BioGRID