DAB1
Gene Ontology Biological Process
- Golgi localization [ISO]
- adult walking behavior [ISO]
- brain development [IEP]
- cell-cell adhesion involved in neuronal-glial interactions involved in cerebral cortex radial glia guided migration [ISO]
- cerebellum structural organization [ISO]
- cerebral cortex cell migration [ISO]
- cerebral cortex development [IEP]
- cerebral cortex radially oriented cell migration [IMP, ISO]
- dendrite development [ISO]
- lateral motor column neuron migration [ISO]
- midgut development [IEP]
- negative regulation of JAK-STAT cascade [ISO]
- negative regulation of astrocyte differentiation [ISO]
- negative regulation of axonogenesis [ISO]
- negative regulation of cell adhesion [ISO]
- neuron migration [IDA, ISO]
- positive regulation of neuron differentiation [ISO]
- positive regulation of protein kinase activity [ISO]
- radial glia guided migration of Purkinje cell [ISO]
- response to drug [IEP]
- small GTPase mediated signal transduction [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
CAPZA1
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Affinity Capture-Western
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins.
Publication
Regulation of the interaction of Disabled-1 with CIN85 by phosphorylation with Cyclin-dependent kinase 5.
Disabled-1 (Dab1) is an adaptor protein mediating Reelin signaling in neuronal migration during brain development. Cyclin-dependent kinase 5 (Cdk5)-p35 is a proline-directed Ser/Thr kinase also involved in neuronal migration. The interaction between Dab1 and Cdk5 is in need of investigation. Dab1 was phosphorylated at Ser400 and Ser491 by Cdk5 in vivo. We search for proteins that interact with Dab1 in ... [more]
Throughput
- Low Throughput
Curated By
- BioGRID