SNX33
Gene Ontology Biological Process
- cleavage furrow formation [IMP]
- endocytosis [IMP]
- endosomal transport [IMP]
- endosome organization [IMP]
- macropinocytosis [IMP]
- membrane tubulation [IDA]
- mitotic cytokinesis [IMP]
- negative regulation of endocytosis [IDA]
- negative regulation of protein localization to cell surface [IDA]
- positive regulation of membrane protein ectodomain proteolysis [IDA]
- positive regulation of protein localization to cell surface [IDA]
- protein import [IDA]
- vesicle organization [IBA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
SNX9
Gene Ontology Biological Process
- cleavage furrow formation [IMP]
- endocytosis [IMP]
- endosomal transport [IMP]
- intracellular protein transport [IMP]
- lipid tube assembly [IDA]
- membrane tubulation [IDA]
- mitotic cytokinesis [IMP]
- positive regulation of GTPase activity [IDA]
- positive regulation of membrane protein ectodomain proteolysis [IDA]
- positive regulation of protein kinase activity [IDA]
- positive regulation of protein oligomerization [IDA]
- receptor-mediated endocytosis [IMP]
- vesicle organization [IBA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Affinity Capture-Western
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins.
Publication
Specific amino acids in the BAR domain allow homodimerization and prevent heterodimerization of sorting nexin 33.
SNX33 (sorting nexin 33) is a homologue of the endocytic protein SNX9 and has been implicated in actin polymerization and the endocytosis of the amyloid precursor protein. SNX33 belongs to the large family of BAR (Bin/amphiphysin/Rvs) domain-containing proteins, which alter cellular protein trafficking by modulating cellular membranes and the cytoskeleton. Some BAR domains engage in homodimerization, whereas other BAR domains ... [more]
Throughput
- Low Throughput
Curated By
- BioGRID