BAIT
SYNJ1
INPP5G, PARK20
synaptojanin 1
GO Process (15)
GO Function (3)
GO Component (2)
Gene Ontology Biological Process
- inositol phosphate dephosphorylation [ISS]
- inositol phosphate metabolic process [TAS]
- neurotransmitter transport [ISS]
- phosphate-containing compound metabolic process [TAS]
- phosphatidylinositol biosynthetic process [TAS]
- phosphatidylinositol dephosphorylation [ISS]
- phosphatidylinositol metabolic process [ISS]
- phospholipid metabolic process [TAS]
- positive regulation of synaptic vesicle uncoating [TAS]
- regulation of synaptic vesicle membrane organization [TAS]
- small molecule metabolic process [TAS]
- synaptic vesicle endocytosis [ISS]
- synaptic vesicle priming [ISS]
- synaptic vesicle transport [ISS]
- synaptic vesicle uncoating [ISS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
SH3GL1
CNSA1, EEN, SH3D2B, SH3P8
SH3-domain GRB2-like 1
GO Process (2)
GO Function (2)
GO Component (1)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Homo sapiens
Protein-peptide
An interaction is detected between a protein and a peptide derived from an interaction partner. This includes phage display experiments.
Publication
The SH3 domains of endophilin and amphiphysin bind to the proline-rich region of synaptojanin 1 at distinct sites that display an unconventional binding specificity.
The proline-rich domain of synaptojanin 1, a synaptic protein with phosphatidylinositol phosphatase activity, binds to amphiphysin and to a family of recently discovered proteins known as the SH3p4/8/13, the SH3-GL, or the endophilin family. These interactions are mediated by SH3 domains and are believed to play a regulatory role in synaptic vesicle recycling. We have precisely mapped the target peptides ... [more]
J. Biol. Chem. Nov. 05, 1999; 274(45);32001-7 [Pubmed: 10542231]
Throughput
- Low Throughput
Curated By
- BioGRID