Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.

Publication

The protein network of HIV budding.

von Schwedler UK, Stuchell M, Mueller B, Ward DM, Chung HY, Morita E, Wang HE, Davis T, He GP, Cimbora DM, Scott A, Kraeusslich HG, Kaplan J, Morham SG, Sundquist WI

HIV release requires TSG101, a cellular factor that sorts proteins into vesicles that bud into multivesicular bodies (MVB). To test whether other proteins involved in MVB biogenesis (the class E proteins) also participate in HIV release, we identified 22 candidate human class E proteins. These proteins were connected into a coherent network by 43 different protein-protein interactions, with AIP1 playing ... [more]

Cell Sep. 19, 2003; 114(6);701-13 [Pubmed: 14505570]

Throughput

Low Throughput

Related interactions

Interaction	Experimental Evidence Code	Dataset	Throughput	Score	Curated By	Notes
CHMP1A CHMP1A	Two-hybrid Two-hybrid Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.	Luck K (2020)	High	-	BioGRID	2722656
CHMP1A CHMP1A	Two-hybrid Two-hybrid Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.	Tsang HT (2006)	Low	-	BioGRID	715000

Curated By

BioGRID

Interaction Summary

CHMP1A

Gene Ontology Biological Process

Gene Ontology Molecular Function

metallopeptidase activity [TAS]protein binding [IPI]protein domain specific binding [IPI]protein homodimerization activity [IPI]zinc ion binding [TAS]

Gene Ontology Cellular Component