BAIT
TRIM45
RNF99, RP11-229A19.2
tripartite motif containing 45
GO Process (0)
GO Function (0)
GO Component (3)
Gene Ontology Cellular Component
Homo sapiens
PREY
UBE2E2
UBCH8
ubiquitin-conjugating enzyme E2E 2
GO Process (6)
GO Function (4)
GO Component (0)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
Functional interactions between ubiquitin E2 enzymes and TRIM proteins.
The TRIM (tripartite motif) family of proteins is characterized by the presence of the tripartite motif module, composed of a RING domain, one or two B-box domains and a coiled-coil region. TRIM proteins are involved in many cellular processes and represent the largest subfamily of RING-containing putative ubiquitin E3 ligases. Whereas their role as E3 ubiquitin ligases has been presumed, ... [more]
Biochem. J. Mar. 01, 2011; 434(2);309-19 [Pubmed: 21143188]
Throughput
- Low Throughput
Curated By
- BioGRID