BAIT
RAD23B
RAD23 homolog B (S. cerevisiae)
GO Process (5)
GO Function (1)
GO Component (3)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- XPC complex [ISO, ISS]
- cytoplasm [ISO]
- nucleoplasm [ISO]
Rattus norvegicus
PREY
PRDX2
Tdpx1
peroxiredoxin 2
GO Process (21)
GO Function (2)
GO Component (4)
Gene Ontology Biological Process
- T cell proliferation [ISO]
- activation of MAPK activity [ISO]
- cellular response to oxidative stress [ISO]
- homeostasis of number of cells [ISO]
- hydrogen peroxide catabolic process [ISO]
- hydrogen peroxide metabolic process [ISO]
- negative regulation of NF-kappaB transcription factor activity [ISO]
- negative regulation of T cell differentiation [ISO]
- negative regulation of extrinsic apoptotic signaling pathway [ISO]
- negative regulation of extrinsic apoptotic signaling pathway in absence of ligand [ISO]
- negative regulation of lipopolysaccharide-mediated signaling pathway [ISO]
- negative regulation of neuron apoptotic process [IMP]
- negative regulation of reactive oxygen species metabolic process [ISO]
- positive regulation of blood coagulation [ISO]
- regulation of apoptotic process [ISO]
- regulation of hydrogen peroxide metabolic process [ISO]
- removal of superoxide radicals [ISO]
- respiratory burst involved in inflammatory response [ISO]
- response to lipopolysaccharide [ISO]
- response to oxidative stress [IMP, ISO]
- thymus development [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Rattus norvegicus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Isolation of mammalian 26S proteasomes and p97/VCP complexes using the ubiquitin-like domain from HHR23B reveals novel proteasome-associated proteins.
Recent studies, mainly in yeast, have identified various cofactors that associate with the 26S proteasome and appear to influence its function. To identify these proteins in different cells and physiological states, we developed a method to gently and rapidly isolate 26S proteasomes and associated proteins without the need for genetic modifications of the proteasome. This method is based on the ... [more]
Biochemistry Mar. 24, 2009; 48(11);2538-49 [Pubmed: 19182904]
Throughput
- Low Throughput
Curated By
- BioGRID