MAPK14
Gene Ontology Biological Process
- 3'-UTR-mediated mRNA stabilization [TAS]
- MyD88-dependent toll-like receptor signaling pathway [TAS]
- MyD88-independent toll-like receptor signaling pathway [TAS]
- RNA metabolic process [TAS]
- Ras protein signal transduction [TAS]
- TRIF-dependent toll-like receptor signaling pathway [TAS]
- activation of MAPK activity [TAS]
- blood coagulation [TAS]
- cell surface receptor signaling pathway [TAS]
- cellular component movement [TAS]
- cellular response to ionizing radiation [IMP]
- cellular response to lipopolysaccharide [IDA]
- cellular response to vascular endothelial growth factor stimulus [IMP]
- chemotaxis [TAS]
- gene expression [TAS]
- innate immune response [TAS]
- intracellular signal transduction [IDA]
- mRNA metabolic process [TAS]
- muscle cell differentiation [TAS]
- neurotrophin TRK receptor signaling pathway [TAS]
- osteoclast differentiation [ISS]
- p38MAPK cascade [ISS]
- peptidyl-serine phosphorylation [ISS]
- platelet activation [TAS]
- positive regulation of blood vessel endothelial cell migration [IMP]
- positive regulation of muscle cell differentiation [TAS]
- positive regulation of myoblast differentiation [ISS]
- positive regulation of myoblast fusion [ISS]
- positive regulation of myotube differentiation [ISS]
- positive regulation of reactive oxygen species metabolic process [IMP]
- regulation of sequence-specific DNA binding transcription factor activity [TAS]
- regulation of transcription from RNA polymerase II promoter [ISS]
- signal transduction [TAS]
- signal transduction in response to DNA damage [IMP]
- stress-activated MAPK cascade [TAS]
- stress-induced premature senescence [IMP]
- toll-like receptor 10 signaling pathway [TAS]
- toll-like receptor 2 signaling pathway [TAS]
- toll-like receptor 3 signaling pathway [TAS]
- toll-like receptor 4 signaling pathway [TAS]
- toll-like receptor 5 signaling pathway [TAS]
- toll-like receptor 9 signaling pathway [TAS]
- toll-like receptor TLR1:TLR2 signaling pathway [TAS]
- toll-like receptor TLR6:TLR2 signaling pathway [TAS]
- toll-like receptor signaling pathway [TAS]
- vascular endothelial growth factor receptor signaling pathway [IMP]
Gene Ontology Molecular Function
TOLLIP
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Affinity Capture-Western
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins.
Publication
Exip, a splicing variant of p38alpha, participates in interleukin-1 receptor proximal complex and downregulates NF-kappaB pathway.
The members of the p38 mitogen-activated protein kinase, especially specific inhibitors such as SB203580 sensitive isoforms, have been shown to play important roles in immune responses as well as in many biological events. In the course of our study to understand how p38 can be responsible for numerous biological phenomena, we have recently identified Exip, an alternative splicing variant of ... [more]
Throughput
- Low Throughput
Curated By
- BioGRID