BAIT
GABRR1
RP11-63L7.1
gamma-aminobutyric acid (GABA) A receptor, rho 1
GO Process (5)
GO Function (0)
GO Component (2)
Gene Ontology Biological Process
Gene Ontology Cellular Component
Homo sapiens
PREY
DNM1L
DLP1, DRP1, DVLP, DYMPLE, EMPF, HDYNIV
dynamin 1-like
GO Process (21)
GO Function (5)
GO Component (11)
Gene Ontology Biological Process
- GTP catabolic process [IDA]
- apoptotic process [TAS]
- cellular component disassembly involved in execution phase of apoptosis [TAS]
- dynamin polymerization involved in mitochondrial fission [IDA]
- membrane fission involved in mitochondrial fission [IDA]
- membrane fusion [IDA]
- mitochondrial fission [IDA, IMP]
- mitochondrial fragmentation involved in apoptotic process [IMP]
- mitochondrion morphogenesis [IMP]
- necroptotic process [IMP]
- peroxisome fission [IDA, IMP]
- positive regulation of apoptotic process [IMP]
- positive regulation of intrinsic apoptotic signaling pathway [IMP]
- positive regulation of mitochondrial fission [TAS]
- positive regulation of protein secretion [IDA]
- positive regulation of release of cytochrome c from mitochondria [IMP]
- protein homotetramerization [IDA]
- regulation of mitochondrion organization [IMP]
- regulation of peroxisome organization [IMP]
- regulation of protein oligomerization [IDA]
- release of cytochrome c from mitochondria [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Tax1-binding protein 1 is expressed in the retina and interacts with the GABA(C) receptor rho1 subunit.
Macromolecular signalling complexes that link neurotransmitter receptors to functionally and structurally associated proteins play an important role in the regulation of neurotransmission. Thus the identification of proteins binding to neurotransmitter receptors describes molecular mechanisms of synaptic signal transduction. To identify interacting proteins of GABA(C) (where GABA is gamma-aminobutyric acid) receptors in the retina, we used antibodies specific for GABA(C) receptor ... [more]
Biochem. J. Jan. 15, 2007; 401(2);429-36 [Pubmed: 16999686]
Throughput
- Low Throughput
Curated By
- BioGRID