BAIT
ARR1
ACR1, YAP8, L000004292, YPR199C
Transcriptional activator of the basic leucine zipper (bZIP) family; required for transcription of genes involved in resistance to arsenic compounds
GO Process (1)
GO Function (3)
GO Component (2)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Saccharomyces cerevisiae (S288c)
PREY
GCN4
AAS101, AAS3, ARG9, amino acid starvation-responsive transcription factor GCN4, L000000683, YEL009C
bZIP transcriptional activator of amino acid biosynthetic genes; activator responds to amino acid starvation; expression is tightly regulated at both the transcriptional and translational levels
GO Process (5)
GO Function (7)
GO Component (1)
Gene Ontology Biological Process
- negative regulation of ribosomal protein gene transcription from RNA polymerase II promoter in response to nutrient levels [IMP]
- negative regulation of transcription from RNA polymerase II promoter [IMP]
- nitrogen catabolite activation of transcription from RNA polymerase II promoter [IMP]
- positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [IDA, IGI, IMP]
- positive regulation of transcription initiation from RNA polymerase II promoter [IGI, IMP]
Gene Ontology Molecular Function- RNA polymerase II transcription factor binding transcription factor activity involved in negative regulation of transcription [IPI]
- RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription [IDA, IMP, IPI]
- RNA polymerase II transcription factor recruiting transcription factor activity [IDA, IMP, IPI]
- TFIID-class binding transcription factor activity [IPI]
- chromatin binding [IDA]
- sequence-specific DNA binding [IDA]
- sequence-specific DNA binding transcription factor activity [IDA, IMP]
- RNA polymerase II transcription factor binding transcription factor activity involved in negative regulation of transcription [IPI]
- RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription [IDA, IMP, IPI]
- RNA polymerase II transcription factor recruiting transcription factor activity [IDA, IMP, IPI]
- TFIID-class binding transcription factor activity [IPI]
- chromatin binding [IDA]
- sequence-specific DNA binding [IDA]
- sequence-specific DNA binding transcription factor activity [IDA, IMP]
Saccharomyces cerevisiae (S288c)
Phenotypic Suppression
A genetic interaction is inferred when mutation or over expression of one gene results in suppression of any phenotype (other than lethality/growth defect) associated with mutation or over expression of another gene.
Publication
One Hand Clapping: detection of condition-specific transcription factor interactions from genome-wide gene activity data.
We present One Hand Clapping (OHC), a method for the detection of condition-specific interactions between transcription factors (TFs) from genome-wide gene activity measurements. OHC is based on a mapping between transcription factors and their target genes. Given a single case-control experiment, it uses a linear regression model to assess whether the common targets of two arbitrary TFs behave differently than ... [more]
Unknown Jul. 25, 2012; 0(0); [Pubmed: 22844089]
Throughput
- Low Throughput
Ontology Terms
- rna accumulation (APO:0000224)
Additional Notes
- gcn4 deletion suppresses transcriptional defect of certain genes in arr1 mutant
Related interactions
Curated By
- BioGRID