BAIT
NGLY1
CDG1V, PNG1, PNGase
N-glycanase 1
GO Process (1)
GO Function (1)
GO Component (1)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Homo sapiens
PREY
NSFL1C
P47, UBX1, UBXD10, UBXN2C, dJ776F14.1, RP4-776F14.2
NSFL1 (p97) cofactor (p47)
GO Process (6)
GO Function (3)
GO Component (5)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Reconstituted Complex
An interaction is detected between purified proteins in vitro.
Publication
The PUB domain functions as a p97 binding module in human peptide N-glycanase.
The AAA ATPase p97 is a ubiquitin-selective molecular machine involved in multiple cellular processes, including protein degradation through the ubiquitin-proteasome system and homotypic membrane fusion. Specific p97 functions are mediated by a variety of cofactors, among them peptide N-glycanase, an enzyme that removes glycans from misfolded glycoproteins. Here we report the three-dimensional structure of the aminoterminal PUB domain of human ... [more]
J. Biol. Chem. Sep. 01, 2006; 281(35);25502-8 [Pubmed: 16807242]
Throughput
- Low Throughput
Curated By
- BioGRID