COMMD1
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
NAIP
Gene Ontology Biological Process
- inhibition of cysteine-type endopeptidase activity involved in apoptotic process [IBA]
- negative regulation of apoptotic process [ISS]
- negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [IDA]
- negative regulation of neuron apoptotic process [TAS]
- nervous system development [TAS]
- protein ubiquitination [IBA]
- regulation of signal transduction [IBA]
- spindle assembly involved in mitosis [IBA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Affinity Capture-Western
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins.
Publication
A novel role for XIAP in copper homeostasis through regulation of MURR1.
XIAP is a potent suppressor of apoptosis that directly inhibits specific members of the caspase family of cysteine proteases. Here we demonstrate a novel role for XIAP in the control of intracellular copper levels. XIAP was found to interact with MURR1, a factor recently implicated in copper homeostasis. XIAP binds to MURR1 in a manner that is distinct from that ... [more]
Throughput
- Low Throughput
Curated By
- BioGRID