BAIT
CCNB1IP1
Gm288, Hei10, mei4
cyclin B1 interacting protein 1
GO Process (5)
GO Function (2)
GO Component (1)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
AKAP9
5730481H23Rik, AKAP-9, AKAP450, AW545847, C79026, G1-448-15, PRKA9, mKIAA0803, mei2-5, repro12
A kinase (PRKA) anchor protein (yotiao) 9
GO Process (2)
GO Function (1)
GO Component (5)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
Evidence Implicating CCNB1IP1, a RING Domain-Containing Protein Required for Meiotic Crossing Over in Mice, as an E3 SUMO Ligase.
The RING domain-containing protein CCNB1IP1 (Cyclin B1 Interacting Protein 1) is a putative ubiquitin E3 ligase that is essential for chiasmata formation, and hence fertility, in mice. Previous studies in cultured cells indicated that CCNB1IP1 targets Cyclin B for degradation, thus playing a role in cell cycle regulation. Mice homozygous for a mutant allele (mei4) of Ccnb1ip1 display no detectable ... [more]
Genes (Basel) Dec. 02, 2010; 1(3);440-451 [Pubmed: 21779533]
Throughput
- Low Throughput
Curated By
- BioGRID