BAIT

CCNB1IP1

Gm288, Hei10, mei4
cyclin B1 interacting protein 1
GO Process (5)
GO Function (2)
GO Component (1)

Gene Ontology Biological Process

Gene Ontology Molecular Function

Gene Ontology Cellular Component

Mus musculus
PREY

OCIAD1

6030432N09Rik, AI481327, AW557942, Asrij, B230209J16Rik, BB021357, Emi2, Imi2, OCIA, TPA018
OCIA domain containing 1
GO Process (0)
GO Function (0)
GO Component (2)

Gene Ontology Cellular Component

Mus musculus

Two-hybrid

Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.

Publication

Evidence Implicating CCNB1IP1, a RING Domain-Containing Protein Required for Meiotic Crossing Over in Mice, as an E3 SUMO Ligase.

Strong ER, Schimenti JC

The RING domain-containing protein CCNB1IP1 (Cyclin B1 Interacting Protein 1) is a putative ubiquitin E3 ligase that is essential for chiasmata formation, and hence fertility, in mice. Previous studies in cultured cells indicated that CCNB1IP1 targets Cyclin B for degradation, thus playing a role in cell cycle regulation. Mice homozygous for a mutant allele (mei4) of Ccnb1ip1 display no detectable ... [more]

Genes (Basel) Dec. 02, 2010; 1(3);440-451 [Pubmed: 21779533]

Throughput

  • Low Throughput

Curated By

  • BioGRID