UCHL1
Gene Ontology Biological Process
- adult walking behavior [IGI, IMP]
- axon target recognition [IMP]
- axon transport of mitochondrion [IMP]
- axonogenesis [IMP]
- cell proliferation [IMP]
- eating behavior [IGI]
- muscle fiber development [IGI]
- negative regulation of MAP kinase activity [ISO]
- neuromuscular process [IMP]
- protein deubiquitination [ISO]
- response to ischemia [IMP]
- sensory perception of pain [ISO]
- ubiquitin-dependent protein catabolic process [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
PTOV1
Gene Ontology Cellular Component
Affinity Capture-Western
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins.
Publication
PTOV1 is associated with UCH-L1 and in response to estrogen stimuli during the mouse oocyte development.
To investigate the biological significance of ubiquitin carboxyl-terminal hydrolase L1 (UCH-L1) involvement in oocyte maturation, we screened for proteins that bound to UCH-L1 in mouse ovaries, and we found that the prostate tumor overexpressed-1 (PTOV1) protein was able to bind to UCH-L1. PTOV1 is highly expressed in prostate cancers and considered as a potential marker for carcinogenesis and the progress ... [more]
Throughput
- Low Throughput
Curated By
- BioGRID