PLCB1
Gene Ontology Biological Process
- G-protein coupled acetylcholine receptor signaling pathway [ISO]
- G2/M transition of mitotic cell cycle [ISO]
- activation of meiosis involved in egg activation [ISO, ISS]
- cerebral cortex development [ISO, ISS]
- fat cell differentiation [ISO]
- glutamate receptor signaling pathway [ISO, ISS]
- insulin-like growth factor receptor signaling pathway [ISO, ISS]
- interleukin-1-mediated signaling pathway [ISO]
- interleukin-12-mediated signaling pathway [ISO]
- interleukin-15-mediated signaling pathway [ISO]
- learning [IEP]
- memory [IEP, ISO]
- negative regulation of monocyte extravasation [ISO, ISS]
- negative regulation of transcription, DNA-templated [ISO, ISS]
- phosphatidylinositol metabolic process [IEP]
- positive regulation of CD24 biosynthetic process [ISO, ISS]
- positive regulation of G1/S transition of mitotic cell cycle [ISO, ISS]
- positive regulation of GTPase activity [ISO]
- positive regulation of JNK cascade [ISO]
- positive regulation of acrosome reaction [ISO]
- positive regulation of developmental growth [ISO, ISS]
- positive regulation of embryonic development [ISO]
- positive regulation of interleukin-12 production [ISO, ISS]
- positive regulation of myoblast differentiation [ISO, ISS]
- positive regulation of transcription, DNA-templated [ISO, ISS]
- regulation of G-protein coupled receptor protein signaling pathway [ISO, ISS]
- regulation of fertilization [ISO]
- response to monosaccharide [IDA]
- response to organonitrogen compound [IEP]
- response to peptide hormone [IDA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
UBC
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Affinity Capture-Western
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins.
Publication
Cell-cycle-dependent PC-PLC regulation by APC/C(Cdc20)-mediated ubiquitin-proteasome pathway.
Phosphatidylcholine-specific phospholipase C (PC-PLC) is involved in the cell signal transduction, cell proliferation, and apoptosis. The mechanism of its action, however, has not been fully understood, particularly, the role of PC-PLC in the cell cycle. In the present study, we found that cell division cycle 20 homolog (Cdc20) and PC-PLC were co-immunoprecipitated reciprocally by either antibody in rat hepatoma cells ... [more]
Throughput
- Low Throughput
Related interactions
Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
---|---|---|---|---|---|---|
UBC PLCB1 | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | Low | - | BioGRID | - |
Curated By
- BioGRID