Reconstituted Complex

An interaction is detected between purified proteins in vitro.

Publication

Ab initio protein modelling reveals novel human MIT domains.

Rigden DJ, Liu H, Hayes SD, Urbe S, Clague MJ

Database searches can fail to detect all truly homologous sequences, particularly when dealing with short, highly sequence diverse protein families. Here, using microtubule interacting and transport (MIT) domains as an example, we have applied an approach of profile-profile matching followed by ab initio structure modelling to the detection of true homologues in the borderline significant zone of database searches. Novel ... [more]

FEBS Lett. Mar. 04, 2009; 583(5);872-8 [Pubmed: 19302785]

Throughput

  • Low Throughput

Related interactions

InteractionExperimental Evidence CodeDatasetThroughputScoreCurated ByNotes
USP8 CHMP1A
Reconstituted Complex
Reconstituted Complex

An interaction is detected between purified proteins in vitro.

Low-BioGRID
-

Curated By

  • BioGRID