BAIT
LNX1
LNX, MPDZ, PDZRN2, UNQ574/PRO1136
ligand of numb-protein X 1, E3 ubiquitin protein ligase
GO Process (0)
GO Function (1)
GO Component (0)
Gene Ontology Molecular Function
Homo sapiens
PREY
STX5
SED5, STX5A
syntaxin 5
GO Process (9)
GO Function (4)
GO Component (6)
Gene Ontology Biological Process
- ER to Golgi vesicle-mediated transport [IBA]
- Golgi disassembly [IDA]
- early endosome to Golgi transport [IMP]
- intracellular protein transport [IBA]
- positive regulation of protein catabolic process [IMP]
- regulation of Golgi organization [IDA]
- retrograde transport, endosome to Golgi [IDA]
- vesicle docking [IBA]
- vesicle fusion [IBA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
Biochemical and computational analysis of LNX1 interacting proteins.
PDZ (Post-synaptic density, 95 kDa, Discs large, Zona Occludens-1) domains are protein interaction domains that bind to the carboxy-terminal amino acids of binding partners, heterodimerize with other PDZ domains, and also bind phosphoinositides. PDZ domain containing proteins are frequently involved in the assembly of multi-protein complexes and clustering of transmembrane proteins. LNX1 (Ligand of Numb, protein X 1) is a ... [more]
PLoS ONE Nov. 17, 2011; 6(11);e26248 [Pubmed: 22087225]
Throughput
- Low Throughput
Curated By
- BioGRID