CDK5
Gene Ontology Biological Process
- axon extension [TAS]
- axon guidance [TAS]
- blood coagulation [TAS]
- cell proliferation [TAS]
- negative regulation of neuron death [IDA]
- negative regulation of proteolysis [IMP]
- negative regulation of transcription, DNA-templated [IMP]
- neuron apoptotic process [TAS]
- neuron differentiation [ISS, TAS]
- neuron migration [TAS]
- neuron projection development [ISS]
- oligodendrocyte differentiation [IDA]
- peptidyl-serine phosphorylation [IDA]
- phosphorylation [IDA]
- positive regulation of actin cytoskeleton reorganization [TAS]
- positive regulation of neuron apoptotic process [ISS]
- regulation of apoptotic process [TAS]
- regulation of cell cycle arrest [TAS]
- regulation of dendritic spine morphogenesis [ISS]
- regulation of synaptic plasticity [ISS, TAS]
- regulation of synaptic vesicle recycling [NAS]
- synapse assembly [TAS]
- synaptic transmission [TAS]
- synaptic vesicle endocytosis [TAS]
- synaptic vesicle exocytosis [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
ODF1
Affinity Capture-Western
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins.
Publication
ODF1 phosphorylation by Cdk5/p35 enhances ODF1-OIP1 interaction.
Cdk5 and p35 are integral components of the sperm tail outer dense fibers (ODFs), which contribute to the distinct morphology and function of the sperm tail. In this study, we sought to characterize and investigate the significance of Cdk5/p35 association with ODFs. We show that ODF2 interacts with Cdk5 and p35 but not with the Cdk5/p35 heterodimer. By using deletion ... [more]
Throughput
- Low Throughput
Curated By
- BioGRID