UBC
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
PEX5
Gene Ontology Biological Process
- cell development [ISO]
- cellular lipid metabolic process [ISO]
- cerebral cortex cell migration [ISO]
- cerebral cortex neuron differentiation [ISO]
- endoplasmic reticulum organization [ISO]
- fatty acid beta-oxidation [ISO]
- isoprenoid biosynthetic process [ISO]
- mitochondrial membrane organization [ISO]
- mitochondrion organization [ISO]
- negative regulation of protein homotetramerization [ISO]
- neuromuscular process [ISO]
- neuron migration [ISO]
- peroxisome organization [ISO]
- positive regulation of multicellular organism growth [ISO]
- protein import into peroxisome matrix [IBA, ISO]
- protein import into peroxisome matrix, docking [IBA, ISO]
- protein import into peroxisome matrix, translocation [ISO]
- protein import into peroxisome membrane [ISO]
- protein targeting to peroxisome [ISO]
- protein tetramerization [ISO]
- very long-chain fatty acid metabolic process [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Affinity Capture-Western
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins.
Publication
AWP1/ZFAND6 functions in Pex5 export by interacting with cys-monoubiquitinated Pex5 and Pex6 AAA ATPase.
During biogenesis of the peroxisome, a subcellular organelle, the peroxisomal-targeting signal 1 (PTS1) receptor Pex5 functions as a shuttling receptor for PTS1-containing peroxisomal matrix proteins. However, the precise mechanism of receptor shuttling between peroxisomes and cytosol remains elusive despite the identification of numerous peroxins involved in this process. Herein, a new factor was isolated by a combination of biochemical fractionation ... [more]
Throughput
- Low Throughput
Additional Notes
- likely ubiquitin conjugate
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| UBC PEX5 | Affinity Capture-Western Affinity Capture-Western An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins. | Low | - | BioGRID | - |
Curated By
- BioGRID