BAIT

LIN7A

Veli1
lin-7 homolog a (C. elegans)
GO Process (3)
GO Function (2)
GO Component (5)
Rattus norvegicus
PREY

MARCH2

MARCH-II, RGD1306395
membrane-associated ring finger (C3HC4) 2, E3 ubiquitin protein ligase
GO Process (1)
GO Function (1)
GO Component (2)

Gene Ontology Biological Process

Gene Ontology Molecular Function

Gene Ontology Cellular Component

Rattus norvegicus

Reconstituted Complex

An interaction is detected between purified proteins in vitro.

Publication

MARCH-II is a syntaxin-6-binding protein involved in endosomal trafficking.

Nakamura N, Fukuda H, Kato A, Hirose S

Membrane-associated RING-CH (MARCH) is a recently identified member of the mammalian E3 ubiquitin ligase family, some members of which down-regulate the expression of immune recognition molecules. Here, we have identified MARCH-II, which is ubiquitously expressed and localized to endosomal vesicles and the plasma membrane. Immunoprecipitation and in vitro binding studies established that MARCH-II directly associates with syntaxin 6. Overexpression of ... [more]

Mol. Biol. Cell Apr. 01, 2005; 16(4);1696-710 [Pubmed: 15689499]

Throughput

  • Low Throughput

Additional Notes

  • figure 10.

Curated By

  • BioGRID