BAIT
CACNB4
CAB4, CACNLB4, EA5, EIG9, EJM, EJM4, EJM6
calcium channel, voltage-dependent, beta 4 subunit
GO Process (7)
GO Function (3)
GO Component (5)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
CBX3
HECH, HP1-GAMMA, HP1Hs-gamma
chromobox homolog 3
GO Process (2)
GO Function (5)
GO Component (10)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Reconstituted Complex
An interaction is detected between purified proteins in vitro.
Publication
The Ca2+ channel beta4c subunit interacts with heterochromatin protein 1 via a PXVXL binding motif.
The β subunits of voltage-gated Ca(2+) channels are best known for their roles in regulating surface expression and gating of voltage-gated Ca(2+) channel α(1) subunits. Recent evidence, however, indicates that these proteins have a variety of Ca(2+) channel-independent functions. For example, on the molecular level, they regulate gene expression, and on the whole animal level, they regulate early cell movements ... [more]
J. Biol. Chem. Mar. 18, 2011; 286(11);9677-87 [Pubmed: 21220418]
Throughput
- Low Throughput
Additional Notes
- figure 4. CSD domain of HP1g. also measured by ITC.
- figure 5. NMR.
Curated By
- BioGRID