Reconstituted Complex

An interaction is detected between purified proteins in vitro.

Publication

Myoferlin regulates vascular endothelial growth factor receptor-2 stability and function.

Bernatchez PN, Acevedo L, Fernandez-Hernando C, Murata T, Chalouni C, Kim J, Erdjument-Bromage H, Shah V, Gratton JP, McNally EM, Tempst P, Sessa WC

Myoferlin and dysferlin are members of the ferlin family of membrane proteins. Recent studies have shown that mutation or genetic disruption of myoferlin or dysferlin promotes muscular dystrophy-related phenotypes in mice, which are the result of impaired plasma membrane integrity. However, no biological functions have been ascribed to myoferlin in non-muscle tissues. Herein, using a proteomic analysis of endothelial cell ... [more]

J. Biol. Chem. Oct. 19, 2007; 282(42);30745-53 [Pubmed: 17702744]

Throughput

  • Low Throughput

Curated By

  • BioGRID