BAIT
TOLLIP
toll interacting protein
GO Process (5)
GO Function (6)
GO Component (3)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Rattus norvegicus
PREY
IL1RAP
IL-1RAcp, Il1racpb
interleukin 1 receptor accessory protein
GO Process (2)
GO Function (5)
GO Component (3)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Rattus norvegicus
Reconstituted Complex
An interaction is detected between purified proteins in vitro.
Publication
Tollip is a mediator of protein sumoylation.
Tollip is an interactor of the interleukin-1 receptor involved in its activation. The endosomal turnover of ubiquitylated IL-1RI is also controlled by Tollip. Furthermore, together with Tom1, Tollip has a general role in endosomal protein traffic. This work shows that Tollip is involved in the sumoylation process. Using the yeast two-hybrid technique, we have isolated new Tollip partners including two ... [more]
PLoS ONE Feb. 10, 2009; 4(2);e4404 [Pubmed: 19198660]
Throughput
- Low Throughput
Additional Notes
- figure 1.
Curated By
- BioGRID