BAIT
SH3KBP1
CD2BP3, CIN85, GIG10, HSB-1, HSB1, MIG18, RP11-345L8.1
SH3-domain kinase binding protein 1
GO Process (6)
GO Function (1)
GO Component (2)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
PDCD6IP
AI480591, AW544830, Aip1, Alix, C76364, Eig2, mKIAA1375, RP24-159F5.1
programmed cell death 6 interacting protein
GO Process (6)
GO Function (6)
GO Component (9)
Gene Ontology Biological Process
- apoptotic process [TAS]
- positive regulation of exosomal secretion [ISO]
- positive regulation of extracellular vesicular exosome assembly [ISO]
- regulation of extracellular vesicular exosome assembly [ISO]
- ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway [ISO]
- viral budding via host ESCRT complex [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
CIN85 interacting proteins in B cells-specific role for SHIP-1.
The Cbl-interacting 85-kDa protein (CIN85) plays an important role as a negative regulator of signaling pathways induced by receptor tyrosine kinases. By assembling multiprotein complexes this versatile adaptor enhances receptor tyrosine kinase-activated clathrin-mediated endocytosis and reduces phosphatidylinositol-3-kinase-induced phosphatidylinositol-3,4,5-trisphosphate production. Here we report the expression of CIN85 in primary splenic B lymphocytes and the B-lymphoma cell lines WEHI 231 and Ba/F3. ... [more]
Mol. Cell Proteomics Oct. 01, 2011; 10(10);M110.006239 [Pubmed: 21725061]
Throughput
- Low Throughput
Additional Notes
- table 1.
Curated By
- BioGRID