BAIT
SH3KBP1
CD2BP3, CIN85, GIG10, HSB-1, HSB1, MIG18, RP11-345L8.1
SH3-domain kinase binding protein 1
GO Process (6)
GO Function (1)
GO Component (2)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
WASL
2900021I12Rik, 3110031I02Rik, N-WASP
Wiskott-Aldrich syndrome-like (human)
GO Process (14)
GO Function (2)
GO Component (5)
Gene Ontology Biological Process
- actin cytoskeleton organization [IMP]
- actin nucleation [TAS]
- cell projection assembly [IMP]
- cellular protein complex localization [IMP]
- membrane budding [ISO]
- membrane invagination [ISO]
- membrane tubulation [ISO]
- positive regulation of clathrin-mediated endocytosis [ISO]
- positive regulation of filopodium assembly [ISO]
- regulation of protein localization [IMP]
- response to bacterium [IMP]
- spindle localization [IMP]
- vesicle organization [ISO]
- vesicle transport along actin filament [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
CIN85 interacting proteins in B cells-specific role for SHIP-1.
The Cbl-interacting 85-kDa protein (CIN85) plays an important role as a negative regulator of signaling pathways induced by receptor tyrosine kinases. By assembling multiprotein complexes this versatile adaptor enhances receptor tyrosine kinase-activated clathrin-mediated endocytosis and reduces phosphatidylinositol-3-kinase-induced phosphatidylinositol-3,4,5-trisphosphate production. Here we report the expression of CIN85 in primary splenic B lymphocytes and the B-lymphoma cell lines WEHI 231 and Ba/F3. ... [more]
Mol. Cell Proteomics Oct. 01, 2011; 10(10);M110.006239 [Pubmed: 21725061]
Throughput
- Low Throughput
Additional Notes
- table 1.
Curated By
- BioGRID