BAIT

SH3KBP1

CD2BP3, CIN85, GIG10, HSB-1, HSB1, MIG18, RP11-345L8.1
SH3-domain kinase binding protein 1
Homo sapiens
PREY

SHKBP1

B930062H15Rik, Sb1
Sh3kbp1 binding protein 1
GO Process (0)
GO Function (1)
GO Component (0)

Gene Ontology Molecular Function

Mus musculus

Affinity Capture-MS

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.

Publication

CIN85 interacting proteins in B cells-specific role for SHIP-1.

Buechse T, Horras N, Lenfert E, Krystal G, Koerbel S, Schuemann M, Krause E, Mikkat S, Tiedge M

The Cbl-interacting 85-kDa protein (CIN85) plays an important role as a negative regulator of signaling pathways induced by receptor tyrosine kinases. By assembling multiprotein complexes this versatile adaptor enhances receptor tyrosine kinase-activated clathrin-mediated endocytosis and reduces phosphatidylinositol-3-kinase-induced phosphatidylinositol-3,4,5-trisphosphate production. Here we report the expression of CIN85 in primary splenic B lymphocytes and the B-lymphoma cell lines WEHI 231 and Ba/F3. ... [more]

Mol. Cell Proteomics Oct. 01, 2011; 10(10);M110.006239 [Pubmed: 21725061]

Throughput

  • Low Throughput

Additional Notes

  • table 1.

Curated By

  • BioGRID