BAIT
NFE2
NF-E2, p45
nuclear factor, erythroid 2
GO Process (8)
GO Function (4)
GO Component (3)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
YAP1
COB1, YAP, YAP2, YAP65, YKI
Yes-associated protein 1
GO Process (8)
GO Function (4)
GO Component (5)
Gene Ontology Biological Process
- cell proliferation [IDA]
- cellular response to DNA damage stimulus [IDA]
- cellular response to gamma radiation [IDA]
- contact inhibition [IDA]
- gene expression [TAS]
- hippo signaling [TAS]
- negative regulation of nucleic acid-templated transcription [IDA]
- transcription initiation from RNA polymerase II promoter [TAS]
Gene Ontology Molecular Function
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
Interaction of WW domains with hematopoietic transcription factor p45/NF-E2 and RNA polymerase II.
NF-E2 is an erythroid-specific transcription factor required for expression of several erythroid-specific genes. By Far-Western blotting and yeast two-hybrid assay, we demonstrate that p45, the large subunit of NF-E2, is capable of binding to a specific set of WW domain-containing proteins, including the ubiquitin ligase hRPF1. This binding is mediated through the interaction between the WW domains and a PY ... [more]
J. Biol. Chem. Sep. 26, 1997; 272(39);24105-8 [Pubmed: 9305852]
Throughput
- Low Throughput
Related interactions
Curated By
- BioGRID