BAIT

CD2BP2

FWP010, LIN1, PPP1R59, Snu40, U5-52K
CD2 (cytoplasmic tail) binding protein 2
Homo sapiens
PREY

WBP11

NPWBP, PPP1R165, SIPP1, WBP-11
WW domain binding protein 11
GO Process (0)
GO Function (4)
GO Component (3)

Gene Ontology Cellular Component

Homo sapiens

Two-hybrid

Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.

Publication

Novel interaction partners of the CD2BP2-GYF domain.

Kofler M, Motzny K, Beyermann M, Freund C

The GYF domain of CD2BP2 serves as an adapter that recognizes proline-rich sequences in intracellular proteins. Although the T cell adhesion molecule CD2 and the core splicing protein SmB/B' were previously shown to interact with CD2BP2-GYF, we are now using a general approach to identify putative GYF domain target sites within the human proteome. The phage display-derived recognition motif for ... [more]

J. Biol. Chem. Sep. 30, 2005; 280(39);33397-402 [Pubmed: 16000308]

Throughput

  • Low Throughput

Related interactions

InteractionExperimental Evidence CodeDatasetThroughputScoreCurated ByNotes
CD2BP2 WBP11
Affinity Capture-MS
Affinity Capture-MS

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.

High368BioGRID
2360303

Curated By

  • BioGRID