BAIT
CD99
HBA71, MIC2, MIC2X, MIC2Y, MSK5X
CD99 molecule
GO Process (0)
GO Function (0)
GO Component (4)
Gene Ontology Cellular Component
Homo sapiens
PREY
FTH1
FHC, FTH, FTHL6, HFE5, PIG15, PLIF, OK/SW-cl.84
ferritin, heavy polypeptide 1
GO Process (8)
GO Function (2)
GO Component (4)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
Identification of cyclophilin A as a CD99-binding protein by yeast two-hybrid screening.
CD99 is a 32kDa surface glycoprotein, which is involved in the migration of leukocytes and the transport of ganglioside GM1 and transmembrane proteins. To identify signaling mechanisms triggered by CD99 engagement, a LexA-based yeast two-hybrid system was utilized to identify proteins interacting with the cytoplasmic domains of CD99. In seven positive clones, we attempted to ascertain whether cyclophilin A (CypA) ... [more]
Immunol. Lett. Sep. 01, 2004; 95(2);155-9 [Pubmed: 15388255]
Throughput
- High Throughput
Curated By
- BioGRID