BAIT
CD99
HBA71, MIC2, MIC2X, MIC2Y, MSK5X
CD99 molecule
GO Process (0)
GO Function (0)
GO Component (4)
Gene Ontology Cellular Component
Homo sapiens
PREY
ANXA2
ANX2, ANX2L4, CAL1H, HEL-S-270, LIP2, LPC2, LPC2D, P36, PAP-IV
annexin A2
GO Process (7)
GO Function (7)
GO Component (14)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
Identification of cyclophilin A as a CD99-binding protein by yeast two-hybrid screening.
CD99 is a 32kDa surface glycoprotein, which is involved in the migration of leukocytes and the transport of ganglioside GM1 and transmembrane proteins. To identify signaling mechanisms triggered by CD99 engagement, a LexA-based yeast two-hybrid system was utilized to identify proteins interacting with the cytoplasmic domains of CD99. In seven positive clones, we attempted to ascertain whether cyclophilin A (CypA) ... [more]
Immunol. Lett. Sep. 01, 2004; 95(2);155-9 [Pubmed: 15388255]
Throughput
- High Throughput
Curated By
- BioGRID